LS-174T/NF-kB Reporter (Luc) stable cell line

LS-174T/NF-kB Reporter (Luc) cells are derived from the human colon cancer LS-174T cell line by stably integration of a NF-kB firefly luciferase reporter construct. The LS174T cells are used to investigate the molecular and cellular mechanisms underlying colon cancer, including tumor growth, metastasis, and drug resistance, as well as testing the efficacy of new anticancer drugs and treatment strategies. LS-174T/NF-kB Reporter (Luc) cells stably express firefly luciferase under the control of the NF-kB response elements, can be used for monitoring the activity of NF-kB signaling pathway.