KLN205 SMAD/TGFbeta Reporter (Luc) stable cell line

KLN205 SMAD/TGFbeta Reporter (Luc) cells are derived from the murine lung squamous cell carcinoma cell line KLN205 by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. KLN205 cell line is a well established model for cancer research, particularly for studying lung cancer mechanisms and potential therapies. KLN205 SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.