LTPA SMAD/TGFbeta Reporter (Luc) stable cell line

LTPA SMAD/TGFbeta Reporter (Luc) cells are derived from the mouse pancreas adenocarcinoma LTPA cell line by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct.LTPA cells are used to investigate the molecular and cellular mechanisms underlying pancreatic cancer, and to evaluate the efficacy of new anticancer drugs and therapies. LTPA SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.