HepG2 SMAD/TGFbeta Reporter (Luc) stable cell line

HepG2 SMAD/TGFbeta Reporter (Luc) cells are derived from the human hepatocarcinoma HepG2 cell line by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. The HepG2 cell line has been widely used as a model system in biomedical research, particularly in studies related to liver biology, drug metabolism, toxicology, hepatitis virus infection and liver cancer. HepG2 SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.