U87-MG SMAD/TGFbeta Reporter (Luc) stable cell line

U87-MG SMAD/TGFbeta Reporter (Luc) cells are derived from the human glioblastoma cell line U87-MG by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. U87-MG cells are used to study the biology of glioblastoma, the mechanisms involved in glioma progression and therapeutic resistance, as well as to evaluate new therapeutic strategies, including chemotherapies, gene therapies, and immunotherapies. U87-MG SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.