KASUMI-3 SMAD/TGFbeta Reporter (Luc) stable cell line

KASUMI-3 SMAD/TGFbeta Reporter (Luc) cells are derived from the human KASUMI-3 myeloblast cell line by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. KASUMI-3 cell line was generated from acute myeloblastic leukemia (AML), has been widely used to study the mechanism of AML and evaluate the effects of new drugs or therapies. KASUMI-3 SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.