RENCA SMAD/TGFbeta Reporter (Luc) stable cell line

RENCA SMAD/TGFbeta Reporter (Luc) cells are derived from the mouse renal adenocarcinoma RENCA cell line by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. The RENCA cell line is a useful model for understanding the biology of renal cell carcinoma and testing therapeutic strategies. RENCA SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.