C6 SMAD/TGFbeta Reporter (Luc) stable cell line

C6 SMAD/TGFbeta Reporter (Luc) cells are derived from the rat C6 glioma cell line by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. C6 cell line has been widely used for studying the molecular mechanisms underlying glioma development and progression, as well as for screening potential drugs for the treatment of gliomas. C6 SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.