HEK293T/ACE2 stable cell line

HEK293T/ACE2 cells are derived from the human immortalized embryonic kidney cell line HEK 293 by stably integration of a constitutive human angiotensin-converting enzyme 2 (ACE2) expression construct. ACE2 is a receptor on the surface of cells that plays a crucial role in the entry of the SARS-CoV-2 virus into cells and causing COVID-19 infection. HEK293T/ACE2 cells stably express ACE2, can be used for studying various aspects of viral infection and developing potential therapeutic interventions such as testing antiviral compounds or vaccines.