Daoy SMAD/TGFbeta Reporter (Luc) stable cell line

Daoy SMAD/TGFbeta Reporter (Luc) cells are derived from the human primary medulloblastoma Daoy cell line by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. Daoy cells has been used as a model system to investigate the molecular mechanisms underlying medulloblastoma development, progression, and response to treatment. Daoy SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.