A20/STAT3 Reporter (Luc) stable cell line

A20/STAT3 Reporter (Luc) cells are derived from the mouse B lymphocyte cell line A20 by stably integration of a STAT3 firefly luciferase reporter construct. A20 cells were derived from a spontaneously arising reticulum cell sarcoma from an aging BALB/c mouse. A20 cells are highly responsive to immunomodulatory antibodies. A20 /STAT3 Reporter (Luc) cells stably express firefly luciferase under the control of the STAT3 response elements, can be used for monitoring the activity of STAT3 signaling pathway.