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LAMA84-s/GFP stable cell line

LAMA84-s/GFP cells are derived from the human chronic myeloid leukemia cell line LAMA84-s by stably integration of a constitutive GFP stably expression construct. The LAMA84-s cell line is sensitive to the tyrosine kinase inhibitor imatinib mesylate, and is paired to the LAMA84-r cell line which is resistant to imatinib. The paired LAMA84-s and LAMA84-r cell lines are useful models of sensitivity and resistance to a tyrosine kinase inhibitor used in the treatment of chronic myeloid leukemia. LAMA84-s/GFP cells stably stably express GFP, can be used for in vitro assays and in vivo imaging.

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