Hep3B SMAD/TGFbeta Reporter (Luc) stable cell line

Hep3B SMAD/TGFbeta Reporter (Luc) cells are derived from the human Hep3B Hepatocellular carcinoma cell line by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. The Hep3B cell line has been widely used in cancer research, particularly in studies related to liver cancer, and drug screening. Hep3B SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.