A549 SMAD/TGFbeta Reporter (Luc) stable cell line

A549 SMAD/TGFbeta Reporter (Luc) cells are derived from the human A549 lung carcinoma cell line by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. A549 cell line has been widely used in cancer research, immunological studies and drug development. A549 SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.