K7M2 SMAD/TGFbeta Reporter (Luc) stable cell line

K7M2 SMAD/TGFbeta Reporter (Luc) cells are derived from the mouse osteosarcoma K7M2 cell line by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. K7M2 cells are used to investigate the molecular mechanisms of osteosarcoma and to explore potential therapeutic approaches. The K7M2 cell line is known for its ability to metastasize to lungs, making it a relevant model for studying tumor metastasis. K7M2 SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.