MCF7 SMAD/TGFbeta Reporter (Luc) stable cell line

MCF7 SMAD/TGFbeta Reporter (Luc) cells are derived from the human breast cancer cell line MCF7 by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. MCF7 cells are estrogen receptor-positive (ER+), making them a valuable model for studying hormone-dependent breast cancers and testing estrogen-related therapies. MCF7 SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.