LL/2 SMAD/TGFbeta Reporter (Luc) stable cell line

LL/2 SMAD/TGFbeta Reporter (Luc) cells are derived from the mouse LL/2 lung carcinoma cell line by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. LL/2 cell line is widely used as a model for metastasis and is useful for studying the mechanisms of cancer chemotherapeutic agents. LL/2 SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.