Daoy/STAT3 Reporter (Luc) stable cell line

Daoy/STAT3 Reporter (Luc) cells are derived from the human primary medulloblastoma Daoy cell line by stably integration of a STAT3 firefly luciferase reporter construct. Daoy cells has been used as a model system to investigate the molecular mechanisms underlying medulloblastoma development, progression, and response to treatment. Daoy/STAT3 Reporter (Luc) cells stably express firefly luciferase under the control of the STAT3 response elements, can be used for monitoring the activity of STAT3 signaling pathway.