BC-1 SMAD/TGFbeta Reporter (Luc) stable cell line

BC-1 SMAD/TGFbeta Reporter (Luc) cells are derived from the human BC-1 B lymphocyte cell line by stably integration of a SMAD/TGFbeta firefly luciferase reporter construct. BC-1 cell line was generated from primary effusion lymphoma (PEL) . BC-1 cells are commonly used to study the biology of PEL and to explore potential treatments for this disease. BC-1 SMAD/TGFbeta Reporter (Luc) cells stably express firefly luciferase under the control of the SMAD/TGFbeta response elements, can be used for monitoring the activity of TGF?/SMAD signaling pathway.