Plitidepsin
Plitidepsin (Aplidine) is a potent anti-cancer agent by targeting eEF1A2 (KD=80 nM) [1]. Plitidepsin possesses antiviral activity and is against SARS-CoV-2 with an IC90 of 0.88 nM. Plitidepsin is usually used for multiple myeloma and advanced cancer research, and has the potential for COVID-19 research[1][2].
Product Specifications
CAS Number
137219-37-5
Product Name Alternative
Aplidine; PM90001
UNSPSC
12352209
Hazard Statement
H225-H302+H312+H332-H319
Target
DNA/RNA Synthesis; SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/plitidepsin.html
Purity
99.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
Molecular Formula
C57H87N7O15
Molecular Weight
1110.34
Precautions
P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P330-P362+P364-P370+P378-P403+P235-P501
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Natural Products
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
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