Maleic acid-d2
Maleic Acid-d2 is the deuterium labeled Maleic Acid[1]. Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes[2][3].
Product Specifications
CAS Number
[24461-33-4]
Product Name Alternative
Maleic-2,3-d2 acid
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; Endogenous Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Purity
99.26
Solubility
H2O : ≥ 100 mg/mL
Smiles
OC(/C([2H])=C([2H])\C(O)=O)=O
Molecular Formula
C4H2D2O4
Molecular Weight
118.08
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Fonda ML, et al. Glutamate decarboxylase. Substrate specificity and inhibition by carboxylic acids. Biochemistry. 1972 Mar 28;11 (7) :1304-9.|[3]Paudyal R, et al. A novel approach in acidic disinfection through inhibition of acid resistance mechanisms Maleic acid-mediated inhibition of glutamate decarboxylase activity enhances acid sensitivity of Listeria monocytogenes. Food Microbiol. 2018 Feb69:96-104.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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