Mal-PEG4-Val-Cit-PAB

Mal-PEG4-Val-Cit-PAB is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-Val-Cit-PAB is used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

CAS Number

[1949793-41-2]

UNSPSC

12352203

Hazard Statement

H302-H315-H319-H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mal-peg4-val-cit-pab.html

Purity

98.87

Solubility

DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OCC1=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O)=O)=O)=O)C=C1

Molecular Formula

C36H55N7O12

Molecular Weight

777.86

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Lorenzo Benatuil, et al. Anti-b7-h3 antibodies and antibody drug conjugates. WO2017214322A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker; Protease Cleavable Linker

Available Sizes

Curated Selection

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