SuO-Val-Cit-PAB-MMAE
SuO-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the peptide SuO-Val-Cit-PAB[1].
Product Specifications
UNSPSC
12352203
Hazard Statement
H300+H330, H340, H360, H370, H372, H412
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SuO-Val-Cit-PAB-MMAE.html
Purity
99.24
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
Molecular Formula
C63H97N11O16
Molecular Weight
1264.51
Precautions
H300+H330, H340, H360, H370, H372, H412
References & Citations
[1]Kamath AV, et al. Preclinical Pharmacokinetic Considerations for the Development of Antibody Drug Conjugates. Pharm Res. 2015 Nov;32 (11) :3470-9.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, stored under nitrogen
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Auristatin
Available Sizes
Frequently Asked Questions
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