Phenyl β-D-glucopyranoside

Phenyl β-D-glucopyranoside is a component isolated from Phellodendron amurense, which has anti-inflammatory and anti-tumor activities. Phenyl β-D-glucopyranoside inhibits nitric oxide (NO) production, and the expression of iNOS and COX-2. Phenyl β-D-glucopyranoside also inhibits the nuclear translocation of NF-κB. Phenyl β-D-glucopyranoside inhibits the expression of pro-inflammatory cytokines and related genes[1][2].

Product Specifications

CAS Number

[1464-44-4]

UNSPSC

12352005

Hazard Statement

H317, H319

Target

COX; MMP; NF-κB; NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/phenyl-β-d-glucopyranoside.html

Purity

99.85

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@H]([C@H]([C@@H]([C@H](O1)CO)O)O)[C@@H]1OC2=CC=CC=C2

Molecular Formula

C12H16O6

Molecular Weight

256.25

Precautions

H317, H319

References & Citations

[1]Hwang SJ, et al. Phenyl-β-D-Glucopyranoside Exhibits Anti-inflammatory Activity in Lipopolysaccharide-Activated RAW 264.7 Cells. Inflammation. 2015;38 (3) :1071-9.|[2]Usabiaga I, et al. Phenyl-β-D-glucopyranoside and Phenyl-β-D-galactopyranoside Dimers: Small Structural Differences but Very Different Interactions[J]. Frontiers in Physics, 2018, 6: 3.