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Empesertib

Empesertib (BAY 1161909) is a potent Mps1 inhibitor, with an IC50 of < 1 nM.

Product Specifications

CAS Number

1443763-60-7

Product Name Alternative

BAY 1161909

UNSPSC

12352005

Hazard Statement

H302

Target

Mps1

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/BAY-1161909.html

Concentration

10mM

Purity

99.22

Solubility

DMSO : ≥ 35 mg/mL

Smiles

FC1=CC=C([C@@H](C)C(NC2=CC=C(C3=CN4N=C(NC5=CC=C(S(C)(=O)=O)C=C5OC)N=C4C=C3)C=C2)=O)C=C1

Molecular Formula

C29H26FN5O4S

Molecular Weight

559.61

Precautions

H302

References & Citations

[1]SCHULZE, Volker, et al. PRODRUG DERIVATIVES OF SUBSTITUTED TRIAZOLOPYRIDINES. WO2014198647A2

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Frequently Asked Questions

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