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Actinine (chloride)

Selected Variant

HY-113270A-01

Size: 50 mg

<font size="3">Actinine (γ-Butyrobetaine) chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat.</font><div><font size="3"><br></font><div><font size="3">Actinine chloride, also known as γ-Butyrobetaine chloride or Deoxycarnitine chloride, is an endogenous and microbial metabolite involved in L-carnitine metabolism. γ-Butyrobetaine is an important intermediate in the gut microbial pathway that converts L-carnitine into trimethylamine (TMA) and subsequently trimethylamine N-oxide (TMAO).</font></div></div>

Product Specifications

CAS Number

<font size="3">6249-56-5</font>

Product Name Alternative

<font size="3">γ-Butyrobetaine (chloride) ; Deoxycarnitine (chloride)</font>

UNSPSC

<font size="3">12352211</font>

Hazard Statement

<font size="3">H302, H315, H319, H335</font>

Target

<font size="3">Endogenous Metabolite</font>

Type

<font size="3">Natural Products</font>

Related Pathways

<font size="3">Metabolic Enzyme/Protease</font>

Applications

<font size="3">COVID-19-immunoregulation</font>

Field of Research

<font size="3">Metabolic Disease; Cardiovascular Disease</font>

Assay Protocol

<font size="3">https://www.medchemexpress.com/actinine-chloride.html</font>

Purity

<font size="3">98.0</font>

Solubility

<font size="3">DMSO : 30 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)</font>

Smiles

<font size="3">C[N+](C)(C)CCCC(O)=O.[Cl-]</font>

Molecular Formula

<font size="3">C7H16ClNO2</font>

Molecular Weight

<font size="3">181.66</font>

Precautions

<font size="3">H302, H315, H319, H335</font>

References & Citations

<font size="3">[1]Koeth RA, et al. γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. Cell Metab. 2014 Nov 4;20 (5) :799-812.|[2]Susumu Ogawa, et al. The Dynamics of Carnitine, γ-butyrobetaine and Trimethylamine N-oxide in Diabetics and the Effects of Changes in Renal Function. Ogawa et al., J Nephrol Ren Dis 2017, 1:2</font>

Shipping Conditions

<font size="3">Room Temperature</font>

Storage Conditions

<font size="3">4°C (Powder, sealed storage, away from moisture)</font>

Scientific Category

<font size="3">Natural Products</font>

Clinical Information

<font size="3">No Development Reported</font>

FAQ

<font size="3"><b><font color="#0015ab">What is Actinine chloride? =&gt; </font></b>Actinine chloride is the chloride salt of γ-butyrobetaine, a metabolite associated with both endogenous carnitine biosynthesis and microbial L-carnitine metabolism. <b><font color="#0015ab">What is γ-Butyrobetaine? </font></b><span style="border-color: oklch(0.922 0 0); outline-color: oklab(0.708 0 0 / 0.5); font-weight: bolder;"><font color="#0015ab" style="border-color: oklch(0.922 0 0); outline-color: oklab(0.708 0 0 / 0.5);">=&gt; </font></span>γ-Butyrobetaine is an intermediate in the microbial metabolism of L-carnitine to TMA, which can subsequently be converted by the host to TMAO. <b><font color="#0015ab">What is the CAS number of Actinine chloride? </font></b><span style="border-color: oklch(0.922 0 0); outline-color: oklab(0.708 0 0 / 0.5); font-weight: bolder;"><font color="#0015ab" style="border-color: oklch(0.922 0 0); outline-color: oklab(0.708 0 0 / 0.5);">=&gt; </font></span>The CAS number is 6249-56-5. <b><font color="#0015ab">What are the main research areas for Actinine chloride? </font></b><span style="border-color: oklch(0.922 0 0); outline-color: oklab(0.708 0 0 / 0.5); font-weight: bolder;"><font color="#0015ab" style="border-color: oklch(0.922 0 0); outline-color: oklab(0.708 0 0 / 0.5);">=&gt; </font></span>It is mainly relevant to gut microbiota, metabolomics, carnitine metabolism, TMA/TMAO research and cardiovascular metabolism.</font>

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