Actinine (chloride)

Actinine (γ-Butyrobetaine) chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat.

Product Specifications

CAS Number

[6249-56-5]

Product Name Alternative

γ-Butyrobetaine (chloride) ; Deoxycarnitine (chloride)

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/actinine-chloride.html

Purity

98.0

Solubility

DMSO : 30 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

C[N+](C)(C)CCCC(O)=O.[Cl-]

Molecular Formula

C7H16ClNO2

Molecular Weight

181.66

Precautions

H302, H315, H319, H335

References & Citations

[1]Koeth RA, et al. γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. Cell Metab. 2014 Nov 4;20 (5) :799-812.|[2]Susumu Ogawa, et al. The Dynamics of Carnitine, γ-butyrobetaine and Trimethylamine N-oxide in Diabetics and the Effects of Changes in Renal Function. Ogawa et al., J Nephrol Ren Dis 2017, 1:2