Voriconazole N-oxide (hydrochloride)

Voriconazole N-oxide (Voriconazole oxynitride) (hydrochloride) is the main metabolite of Voriconazole (HY-76200), a widely used triazole antibiotic (fungal) . Voriconazole N-oxide (hydrochloride) provides information on the patient's drug metabolism capacity[1].

Product Specifications

Product Name Alternative

Voriconazole oxynitride (hydrochloride)

UNSPSC

12352005

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/voriconazole-n-oxide-hydrochloride.html

Purity

99.31

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

C[C@@H](C1=NC=[N+]([O-])C=C1F)[C@@](O)(C2=C(C=C(C=C2)F)F)CN3C=NC=N3.Cl

Molecular Formula

C16H15ClF3N5O2

Molecular Weight

401.77

References & Citations

[1]Christelle Boglione-Kerrien, et al. Contribution of voriconazole N-oxide plasma concentration measurements to voriconazole therapeutic drug monitoring in patients with invasive fungal infection. Mycoses. 2023 May;66 (5) :396-404.