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MAT2A inhibitor 2

MAT2A inhibitor 2 is an inhibitor of methionine adenosine transferase 2A (MAT2A) with oral activity. MAT2A inhibitor 2 can be used in osteoporosis study[1]

Product Specifications

CAS Number

13299-99-5

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Methionine Adenosyltransferase (MAT) ; NF-κB; p38 MAPK

Type

Reference compound

Related Pathways

Epigenetics; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/MAT2A_inhibitor_1.html

Purity

99.71

Solubility

DMSO : 75 mg/mL (ultrasonic)

Smiles

O=C1C(C)=CC(C2=CC=CC(OC)=C2)=NN1CCN3CCOCC3.[H]Cl

Molecular Formula

C18H24ClN3O3

Molecular Weight

365.85

Precautions

H302, H315, H319, H335

References & Citations

[1]Kang H, et al. Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss. FASEB J. 2022 Feb;36 (2) :e22167.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Frequently Asked Questions

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