MAT2A inhibitor 2
MAT2A inhibitor 2 is an inhibitor of methionine adenosine transferase 2A (MAT2A) with oral activity. MAT2A inhibitor 2 can be used in osteoporosis study[1]
Product Specifications
CAS Number
[13299-99-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Methionine Adenosyltransferase (MAT) ; NF-κB; p38 MAPK
Type
Reference compound
Related Pathways
Epigenetics; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MAT2A_inhibitor_1.html
Purity
99.71
Solubility
DMSO : 75 mg/mL (ultrasonic)
Smiles
O=C1C(C)=CC(C2=CC=CC(OC)=C2)=NN1CCN3CCOCC3.[H]Cl
Molecular Formula
C18H24ClN3O3
Molecular Weight
365.85
Precautions
H302, H315, H319, H335
References & Citations
[1]Kang H, et al. Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss. FASEB J. 2022 Feb;36 (2) :e22167.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
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