MAT2A inhibitor 2

13299-99-5

12352005

H302, H315, H319, H335

Methionine Adenosyltransferase (MAT) ; NF-κB; p38 MAPK

Reference compound

Epigenetics; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB

Cancer-programmed cell death

Cancer

https://www.medchemexpress.com/MAT2A_inhibitor_1.html

99.71

DMSO : 75 mg/mL (ultrasonic)

O=C1C(C)=CC(C2=CC=CC(OC)=C2)=NN1CCN3CCOCC3.[H]Cl

C18H24ClN3O3

365.85

H302, H315, H319, H335

[1]Kang H, et al. Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss. FASEB J. 2022 Feb;36 (2) :e22167.

Room Temperature

4°C (Powder, sealed storage, away from moisture)

Reference compound1

Phase 1