4-Boc-amino-2,2-dimethylbutyric acid
4-Boc-amino-22-dimethylbutyric acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
153039-17-9
UNSPSC
12352211
Hazard Statement
H302
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-boc-amino-2-2-dimethylbutyric-acid.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C(O)C(C)(C)CCNC(OC(C)(C)C)=O
Molecular Formula
C11H21NO4
Molecular Weight
231.29
Precautions
H302
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
Available Sizes
Frequently Asked Questions
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