4-Boc-amino-2,2-dimethylbutyric acid

4-Boc-amino-22-dimethylbutyric acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[153039-17-9]

UNSPSC

12352211

Hazard Statement

H302

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/4-boc-amino-2-2-dimethylbutyric-acid.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(O)C(C)(C)CCNC(OC(C)(C)C)=O

Molecular Formula

C11H21NO4

Molecular Weight

231.29

Precautions

H302

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers

Available Sizes

Curated Selection

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