Elgodipine
Elgodipine (IQB-875 free base) is an orally active dihydropyridine calcium antagonist and an antianginal compound. Elgodipine inhibits both T- and L-type calcium channels (IC50: 32 and 2.3 nM) . Elgodipine lowers systemic vascular resistance and improves systolic cardiac function[1][2][3].
Product Specifications
CAS Number
119413-55-7
Product Name Alternative
IQB-875 (free base)
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/elgodipine.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C)NC(C)=C(C(OC(C)C)=O)C1C2=C3OCOC3=CC=C2)OCCN(CC4=CC=C(F)C=C4)C
Molecular Formula
C29H33FN2O6
Molecular Weight
524.58
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
L-type calcium channel; T-type calcium channel
Available Sizes
Frequently Asked Questions
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