Recombinant Human CADM-140/MDA5 Protein
MDA5 / IFIH1 is the CADM-140 autoantigen, involved in clinically amyopathic dermatomyositis (CADM) . This is a chronic inflammatory disorder that shows typical skin manifestations of dermatomyositis but has no or little evidence of clinical myositis. Anti-CADM-140 antibodies appear to be specific to dermatomyositis, especially CADM. Patients with anti-CADM-140 antibodies frequently develop life-threatening acute progressive interstitial lung disease (ILD) .
Product Specifications
Product Name Alternative
Accession Number
Q9BYX4
Expression System
Confidential
Nature
Recombinant
Applications
As a diagnostic tool for Clinically Amyopathic Dermatomyositis (CADM) .
Stability
Endotoxin
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Form
Liquid
Buffer
20mM Tris-HCl, pH 8.0, 100mM NaCl, 1mM DTT, 10% Glycerol.
Shipping Conditions
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Notes
For research use only.
Species
Homo sapiens (Human)
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