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Recombinant Human CXCL9/MIG Protein (Trx Tag)

Product Specifications

Background

Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions by interacting with the chemokine receptor CXCR3. CXCL9 acts as a Th1 (type 1 helper T) cell chemoattractant and plays a role in the growth, activation and movement of cells associated with immune and inflammatory responses, and in tumour growth inhibition. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4.

Abbreviation

CXCL9

Synonyms

Crg; CXCL; SCYB; C-X-C Motif Chemokine; Small-Inducible Cytokine B; Chemokine (C-X-C motif) ligand; CXCL9; CMK; Humig; MIG; SCYB9; crg-10; Chemokine (C-X-C motif) ligand 9; C-X-C Motif Chemokine 9; Gamma-Interferon-Induced Monokine; Monokine induced by gamma interferon; Monokine Induced by Interferon-Gamma; Monokine Induced by Interferon-γ; Small-Inducible Cytokine B9

UniProt

Q07325

Accession Number

Q07325

Expression System

E.coli

Tag

N-Trx

Sequence

Thr23-Thr125

Field of Research

Immunology

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

31.3 kDa

Observed Molecular Weight

32 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Species

Human

Available Sizes

Curated Selection

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