Ranitidine S-oxide (Standard)

Ranitidine S-oxide (Standard) is the analytical standard of Ranitidine S-oxide. This product is intended for research and analytical applications. Ranitidine S-oxide is the metabolite of Ranitidine (HY-B0693) . Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion[1][2].

Product Specifications

CAS Number

[73851-70-4]

UNSPSC

12352005

Hazard Statement

H317-H334-H335

Target

Drug Metabolite; Reference Standards

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ranitidine-s-oxide-standard.html

Smiles

O=[N+](/C=C(NCCS(CC1=CC=C(CN(C)C)O1)=O)\NC)[O-]

Molecular Formula

C13H22N4O4S

Molecular Weight

330.40

Precautions

P261-P271-P272-P280-P284-P302+P352-P304+P340-P362+P364-P405-P501

References & Citations

[1]Cross DM, et al. Kinetics of ranitidine metabolism in dog and rat isolated hepatocytes. Xenobiotica. 1995 Apr;25 (4) :367-75.|[2]Leucuta A, et al. A pharmacokinetic interaction study between omeprazole and the H2-receptor antagonist ranitidine. Drug Metabol Drug Interact. 2004;20 (4) :273-81.