SLF-amido-C2-COOH

SLF-amido-C2-COOH (PROTAC FKBP12-binding moiety 1) is a synthetic ligand for FKBP (SLF) . SLF-amido-C2-COOH (PROTAC FKBP12-binding moiety 1) can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[1092369-24-8]

Product Name Alternative

PROTAC FKBP12-binding moiety 1

UNSPSC

12352005

Target

FKBP; Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Target_Protein-binding_moiety_13.html

Purity

99.63

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)CCC(NC1=CC=CC([C@H](OC([C@H]2N(C(C(C(C)(C)CC)=O)=O)CCCC2)=O)CCC3=CC=C(OC)C(OC)=C3)=C1)=O

Molecular Formula

C34H44N2O9

Molecular Weight

624.72

References & Citations

[1]Dunyak BM, et al. Selective Targeting of Cells via Bispecific Molecules That Exploit Coexpression of TwoIntracellular Proteins. ACS Chem Biol. 2015 Nov 20;10 (11) :2441-7.