DAPTA
Product Specifications
UNSPSC Description
DAPTA is a synthetic peptide, functions as a viral entry inhibitor by targeting selectively CCR5, and shows potent anti-HIV activities.
Target Antigen
CCR; HIV
Type
Peptides
Related Pathways
Anti-infection;GPCR/G Protein;Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection; Endocrinology
Assay Protocol
https://www.medchemexpress.com/DAPTA.html
Purity
99.85
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](C)N)=O)CO)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CC(N)=O)=O)C(N[C@@H]([C@@H](C)O)C(N)=O)=O)C=C1
Molecular Weight
856.88
References & Citations
[1]Pollicita M, et al. Profound anti-HIV-1 activity of DAPTA in monocytes/macrophages and inhibition of CCR5-mediated apoptosis in neuronal cells. Antivir Chem Chemother. 2007;18(5):285-95.|[2]Polianova MT, et al. Chemokine receptor-5 (CCR5) is a receptor for the HIV entry inhibitor peptide T (DAPTA). Antiviral Res. 2005 Aug;67(2):83-92.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1034/DAPTA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1034/DAPTA-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
106362-34-9
Available Sizes
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