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1,4-Di (3-hydroxypropoxy) butane

1,4-Di (3-hydroxypropoxy) butane is the linker of PROTAC Aster-A degrader-1 and can be used for the synthesis of PROTAC[1].

Product Specifications

CAS Number

2052305-98-1

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/1-4-di-3-hydroxypropoxy-butane.html

Solubility

10 mM in DMSO

Smiles

OCCCOCCCCOCCCO

Molecular Formula

C10H22O4

Molecular Weight

206.28

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]He N, et al. Fluorescent probes and degraders of the sterol transport protein Aster-A. Bioorg Med Chem. 2024 Apr 1;103:117673. doi: 10.1016/j.bmc.2024.117673. Epub 2024 Mar 2. PMID: 38518734.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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