1,4-Di (3-hydroxypropoxy) butane
1,4-Di (3-hydroxypropoxy) butane is the linker of PROTAC Aster-A degrader-1 (HY-D233) and can be used for the synthesis of PROTAC[1].
Product Specifications
CAS Number
[2052305-98-1]
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-4-di-3-hydroxypropoxy-butane.html
Solubility
10 mM in DMSO
Smiles
OCCCOCCCCOCCCO
Molecular Formula
C10H22O4
Molecular Weight
206.28
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]He N, et al. Fluorescent probes and degraders of the sterol transport protein Aster-A. Bioorg Med Chem. 2024 Apr 1;103:117673. doi: 10.1016/j.bmc.2024.117673. Epub 2024 Mar 2. PMID: 38518734.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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