Bz-rA Phosphoramidite

Bz-rA Phosphoramidite is used for ribonucleotides modification[1].

Product Specifications

CAS Number

[104992-55-4]

Product Name Alternative

DMT-2'O-TBDMS-rA (bz) Phosphoramidite

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/bz-ra-phosphoramidite.html

Concentration

10mM

Purity

99.03

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](N5C6=NC=NC(NC(C7=CC=CC=C7)=O)=C6N=C5)O4

Molecular Formula

C53H66N7O8PSi

Molecular Weight

988.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Elise Malek-Adamian, et al. 4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. J Am Chem Soc. 2017 Oct 18;139 (41) :14542-14555.