HBX 19818
Product Specifications
UNSPSC Description
HBX 19818 is a specific inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 28.1 μM.
Target Antigen
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/HBX-19818.html
Solubility
1M HCl : 100 mg/mL (ultrasonic;adjust pH to 1 with HCl)|DMSO : 20 mg/mL (ultrasonic)
Smiles
CN(CCCNC(C1=CC=C(N=C(CCCC2)C2=C3Cl)C3=C1)=O)CC4=CC=CC=C4
Molecular Weight
421.96
References & Citations
[1]Reverdy C, et al. Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme. Chem Biol. 2012 Apr 20;19(4):467-77.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-17540/HBX-19818-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-17540/HBX-19818-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1426944-49-1
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
LATS1, NT (LATS1, WARTS, Serine/threonine-protein kinase LATS1, Large tumor suppressor homolog 1, WARTS protein kinase) (APC)