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Brilliant Yellow

Brilliant Yellow, a diazo-containing sulfonic aci, is also a potent VGLUT-specific inhibitor. Brilliant Yellow is membrane-impermeable. However, there are some Brilliant Yellow analogs with low cytotoxicity and cell penetration. Brilliant Yellow analogs work on glutamatergic transmission in hippocampal neurons[1].

Product Specifications

CAS Number

[3051-11-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

GLUT

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/brilliant-yellow.html

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=S(C1=CC(/N=N/C2=CC=C(O)C=C2)=CC=C1/C=C/C3=CC=C(/N=N/C4=CC=C(O)C=C4)C=C3S(=O)(O[Na])=O)(O[Na])=O

Molecular Formula

C26H18N4Na2O8S2

Molecular Weight

624.55

Precautions

H302, H315, H319, H335

References & Citations

[1]Kehrl J, et al. Vesicular Glutamate Transporter Inhibitors: Structurally Modified Brilliant Yellow Analogs. Neurochem Res. 2017 Jun;42 (6) :1823-1832.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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