APC Anti-Human CD7 Antibody[HIT7]
Product Specifications
Background
CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly) . CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.
Abbreviation
CD7
Gene ID
924
UniProt
P09564
Host
Mouse
Reactivity
Human
Target
CD7; GP40; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; TP41
Clonality
Monoclonal
Clone
HIT7
Conjugation
APC
Applications
FCM
Field of Research
Costimulatory Molecules; Immunology
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG1, κ
Available Sizes
Frequently Asked Questions
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