Caspase 8 Processing Enzyme Substrate

<strong>Caspase 8 Processing Enzyme Substrate</strong>_x000D_ <strong>Catalog number:</strong> B2013010_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 2 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 730.7 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Granzyme B Substrate, Caspase 3 Processing Enzyme Substrate, Caspase 8 Processing Enzyme Substrate_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Chehade H, Fox A, Mor GG, Alvero AB. Determination of Caspase Activation by Western Blot Methods Mol Biol. 2021;2255:1-12._x000D_ 2: Dang DT, van Onzen AHAM, Dorland YL, Brunsveld L. Cucurbit8uril Reactivation of an Inactivated Caspase-8 Mutant Reveals Differentiated Enzymatic Substrate Processing Chembiochem. 2018 Dec 4;19(23):2490-2494._x000D_ 3: O'Donnell MA, Perez-Jimenez E, Oberst A, Ng A, Massoumi R, Xavier R, Green DR, Ting AT. Caspase 8 inhibits programmed necrosis by processing CYLD Nat Cell Biol. 2011 Oct 30;13(12):1437-42._x000D_ 4: Pop C, Oberst A, Drag M, Van Raam BJ, Riedl SJ, Green DR, Salvesen GS. FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity Biochem J. 2011 Feb 1;433(3):447-457._x000D_ 5: Rank KB, Mildner AM, Leone JW, Koeplinger KA, Chou KC, Tomasselli AG, Heinrikson RL, Sharma SK. [W206R]-procaspase 3: an inactivatable substrate for caspase 8 Protein Expr Purif. 2001 Jul;22(2):258-66._x000D_ 6: Niikura Y, Nonaka T, Imajoh-Ohmi S. Monitoring of caspase-8/FLICE processing and activation upon Fas stimulation with novel antibodies directed against a cleavage site for caspase-8 and its substrate, FLICE-like inhibitory protein (FLIP) J Biochem. 2002 Jul;132(1):53-62._x000D_ 7: Bando M, Hasegawa M, Tsuboi Y, Miyake Y, Shiina M, Ito M, Handa H, Nagai K, Kataoka T. The mycotoxin penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8 in death-inducing signaling complex J Biol Chem. 2003 Feb 21;278(8):5786-93._x000D_ 8: Bonneau L, Ge Y, Drury GE, Gallois P. What happened to plant caspases? J Exp Bot. 2008;59(3):491-9._x000D_ 9: Dehkordi MH, Munn RGK, Fearnhead HO. Non-Canonical Roles of Apoptotic Caspases in the Nervous System Front Cell Dev Biol. 2022 Feb 23;10:840023._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/9766499">10: King D, Pringle JH, Hutchinson M, Cohen GM. Processing/activation of caspases, -3 and -7 and -8 but not caspase-2, in the induction of apoptosis in B-chronic lymphocytic leukemia cells Leukemia. 1998 Oct;12(10):1553-60. </a>_x000D_ _x000D_ <strong>Products Related to Caspase 8 Processing Enzyme Substrate can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>