MLS0315771
MLS0315771 is a potent and biologically active competitive phosphomannose isomerase (MPI) inhibitor, with an IC50 ~1 μM and a Ki of 1.4 μM.
Product Specifications
CAS Number
[727664-91-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/MLS0315771.html
Purity
99.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC1=CC=C2C(SN(C3=C(C)C=CC(C)=C3)C2=O)=C1
Molecular Formula
C15H12FNOS
Molecular Weight
273.33
Precautions
H302, H315, H319, H335
References & Citations
[1]Sharma V, et al. Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts. J Biol Chem. 2011 Nov 11;286 (45) :39431-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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