Protein Kinase C (19-35) Peptide

Protein Kinase C (19-35) Peptide is the PKC pseudosubstrate inhibitor/region. Protein Kinase C (19-35) Peptide possibly blocks the substrate-binding site in its kinase domain, makes the cytoplasmic form of PKC inactive[1][2].

Product Specifications

CAS Number

[309247-48-1]

UNSPSC

12352209

Target

PKC

Type

Peptides

Related Pathways

Epigenetics; TGF-beta/Smad

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/protein-kinase-c-19-35-peptide.html

Purity

99.90

Solubility

H2O : ≥ 100 mg/mL

Smiles

NCCCC[C@@H](C(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@H](C(C)C)NC([C@H](CC(N)=O)NC([C@H](CCCCN)NC([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](C)NC(CNC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@@H](NC([C@@H](N)CCCNC(N)=N)=O)CC1=CC=CC=C1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC2=CN=CN2)=O)=O)=O

Molecular Formula

C89H153N33O22

Molecular Weight

2037.40

References & Citations

[1]Steiner J, et al. The effect of acute ethanol (EtOH) exposure on protein kinase C (PKC) activity in anterior pituitary. Alcohol. 1997 May-Jun;14 (3) :209-11. |[2]Mosior M, et al. Peptides that mimic the pseudosubstrate region of protein kinase C bind to acidic lipids in membranes. Biophys J. 1991 Jul;60 (1) :149-59. |[3]Laudanna C, et al. Evidence of zeta protein kinase C involvement in polymorphonuclear neutrophil integrin-dependent adhesion and chemotaxis. J Biol Chem. 1998 Nov 13;273 (46) :30306-15.