Tebipenem

Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa.

Product Specifications

CAS Number

[161715-21-5]

Product Name Alternative

LJC 11036

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Tebipenem.html

Purity

99.69

Solubility

DMSO : 33.33 mg/mL (ultrasonic) |H2O : 5.83 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C(N1C2=O)=C(SC3CN(C4=NCCS4)C3)[C@H](C)[C@]1([H])[C@@]2([H])[C@H](O)C)O

Molecular Formula

C16H21N3O4S2

Molecular Weight

383.49

Precautions

H302, H315, H319, H335

References & Citations

[1]Hazra S, et al. Tebipenem, a new carbapenem antibiotic, is a slow substrate that inhibits the β-lactamase from Mycobacterium tuberculosis. Biochemistry. 2014 Jun 10;53 (22) :3671-8|[2]Seenama C, et al. In vitro activity of tebipenem against Burkholderia pseudomallei. Int J Antimicrob Agents. 2013 Oct;42 (4) :375.|[3]Li H, et al. In vitro antibacterial activities of two novel oral antibiotics, tebipenem and cefditoren, and other comparators against community-acquired respiratory tract infection-associated bacterial pathogens: A multicentre study in China. Int J Antimicrob Agents. 2014 Jan;43 (1) :92-3.