(E) -Cardamonin
(E) -Cardamonin ((E) -Cardamomin) is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM.
Product Specifications
CAS Number
19309-14-9
Product Name Alternative
(E) -Cardamomin; (E) -Alpinetin chalcone
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; TRP Channel
Type
Natural Products
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Cardamonin.html
Purity
99.84
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
O=C(C1=C(OC)C=C(O)C=C1O)/C=C/C2=CC=CC=C2
Molecular Formula
C16H14O4
Molecular Weight
270.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Wang S, et al. Cardamonin, a Novel Antagonist of hTRPA1 Cation Channel, Reveals Therapeutic Mechanism of Pathological Pain. Molecules. 2016 Aug 29;21 (9) . pii: E1145.|[2]Park MK, et al. Novel anti-nociceptive effects of cardamonin via blocking expression of cyclooxygenase-2 andtransglutaminase-2. Pharmacol Biochem Behav. 2014 Mar;118:10-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040204-100 1x 100 µL
Complement C4d (C4D204), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740040-500 1x 500 µL
CD35 / CR1 (E11), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880679-500 1x 500 µL
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680204-100 1x 100 µL
Complement C4d (C4D204), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details