7-MAD-MDCPT

7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs) [1].

Product Specifications

CAS Number

[765871-81-6]

UNSPSC

12352203

Hazard Statement

H301

Target

ADC Payload

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/7-mad-mdcpt.html

Purity

98.80

Solubility

DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

NCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(OCO6)=C6C=C51

Molecular Formula

C22H19N3O6

Molecular Weight

421.40

Precautions

H301

References & Citations

[1]Jeffrey S, et, al. Camptothecin peptide conjugates. WO2019195665A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Camptothecins

Available Sizes

Curated Selection

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