7-MAD-MDCPT
7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[765871-81-6]
UNSPSC
12352203
Hazard Statement
H301
Target
ADC Payload
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/7-mad-mdcpt.html
Purity
98.80
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(OCO6)=C6C=C51
Molecular Formula
C22H19N3O6
Molecular Weight
421.40
Precautions
H301
References & Citations
[1]Jeffrey S, et, al. Camptothecin peptide conjugates. WO2019195665A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Camptothecins
Available Sizes
Curated Selection
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